Invitrogen™ LFNG Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA584802

Product Code. 16311755

Description

Immunogen sequence: TKKFHRARLD LLLETWISRH KEMTFIFTDG EDEALARHTG NVVITNCSAA H Highest antigen sequence indentity to the following orthologs: Rat - 92%, Mouse - 88%.

LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).

Specifications

• Antigen: LFNG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LFNG
• Gene Alias: AW061165; beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; LFNG; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; lunatic fringe; lunatic fringe gene homolog; MGC128664 protein; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; SCDO3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3955
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NES3
• Gene Symbols: LFNG
• Immunogen: Recombinant protein corresponding to Human LFNG. Recombinant protein control fragment (Product #RP-103673).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG