missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18045682

Tocris Bioscience™ Lestaurtinib
GREENER_CHOICE

Product Code. 18045682
Click to view available options
Quantity:
1 mg
Unit Size:
1mg
This item is not returnable. View return policy

Product Code. 18045682

Brand: Tocris Bioscience™ 3395/1

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM, respectively). Also inhibits Aurora kinase A and B (IC50 values are 8.1 and 2.3 nM, respectively) and prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo.
TRUSTED_SUSTAINABILITY

Specifications

CAS 111358-88-4
Quantity 1 mg
Molecular Formula C26H21N3O4
Formula Weight 439.46
Purity >99%
Molecular Weight (g/mol) 439.47
Chemical Name or Material Lestaurtinib
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.