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Lenalidomide hemihydrate, MedChemExpress

Product Code. 16461966
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500 mg
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500mg
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Product Code. 16461966

Brand: Medchem Express HYA0003B

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Description

MedChemExpress Lenalidomide hemihydrate (CC-5013 hemihydrate), a derivative of Thalidomide, acts as molecular glue.

Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate (CC-5013 hemihydrate) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate (CC-5013 hemihydrate) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

Specifications

Chemical Name or Material Lenalidomide hemihydrate
CAS 847871-99-2
Color Pink
Purity Grade Notes Research
Molecular Formula C13H14N3O3.5
Quantity 500 mg
Synonym CC-5013 hemihydrate
Solubility Information DMSO : 50 mg/mL (186.38 mM; Need ultrasonic) ∣H2O : 0.1 mg/mL (0.37 mM; Need ultrasonic)
SMILES O=C1N(C2C(NC(CC2)=O)=O)CC3=C(N)C=CC=C31.[0.5 H2O]
Molecular Weight (g/mol) 268.27
Formula Weight 268.27
Percent Purity 98.8%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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