Invitrogen™ LEF1 Recombinant Rabbit Monoclonal Antibody (9I9T4)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA535521

Product Code. 17106183

Description

Immunogen sequence: LADIKSSLVN ESEIIPASNG HEVARQAQTS QEPYHDKARE HPDDGKHPDG GLYNKGPSYS SYSGYIMMPN MNNDPYMSNG SLSPPIPRTS NKVPVVQPSH A.

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: LEF1
• Classification: Recombinant Monoclonal
• Concentration: 0.28 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P27782, Q9UJU2
• Gene Symbols: LEF1
• Immunogen: Recombinant protein for a sequence within amino acids 50-150 of human LEF1 (Q9UJU2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 9I9T4
• Conjugate: Unconjugated
• Gene: LEF1
• Gene Alias: 3000002B05; AI451430; DKFZp586H0919; FLJ46390; HGNC:6551; HMG Binding Domain; LEF1; Lef-1; lymphoid enhancer binding factor 1; lymphoid enhancer binding factor 1 short isoform; lymphoid enhancer-binding factor 1; OTTHUMP00000219736; OTTHUMP00000219737; T cell-specific transcription factor 1-alpha; TCF10; TCF1ALPHA; TCF1-alpha; TCF7L3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16842, 51176
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid