Invitrogen™ LCLAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA561911

Product Code. 15769711

Description

Immunogen sequence: ICLKASLKGV PGFGWAMQAA AYIFIHRKWK DDKSHFEDMI DYFCDIHEPL QLLIFPEGTD LTENSKSRSN AFAEKNGLQK YEYV Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling. Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol-3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3- phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:16620771). Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities (PubMed:19075029). Required for establishment of the hematopoietic and endothelial lineages. [UniProt].

Specifications

• Antigen: LCLAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LCLAT1
• Gene Alias: 1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGP acyltransferase 8; 1-AGPAT 8; 1AGPAT8; Acyl-CoA:lysocardiolipin acyltransferase 1; Agpat8; AI181996; Alcat1; Gm91; HSRG1849; LCLAT1; Lycat; lysocardiolipin acyltransferase 1; RGD1565906; UNQ1849; UNQ1849/PRO3579
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 253558
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: Lot-Specific
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6UWP7
• Gene Symbols: LCLAT1
• Immunogen: Recombinant protein corresponding to Human LCLAT1. Recombinant protein control fragment (Product #RP-95707).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG