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Lck Inhibitor, MedChemExpress

Product Code. 16477707
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Product Code. 16477707

Brand: Medchem Express HY12072

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Description

MedChemExpress Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.

Lck Inhibitor is a potent, orally active Lck (lymphocyte specific kinase) inhibitor with IC50s of 7, 2.1, 4.2 and 200 nM for Lck, Lyn, Src and Syk kinases, respectively. Lck Inhibitor shows >1000-fold selectivity for Lck over MAPK, CDK and RSK family representatives. Lck Inhibitor inhibits T cell proliferation and in vivo models of arthritis.

Specifications

Chemical Name or Material Lck Inhibitor
CAS 847950-09-8
Color Yellow
Purity Grade Notes Research
Molecular Formula C31H30N8O
Quantity 5 mg
Solubility Information DMSO : 100 mg/mL (188.46 mM; Need ultrasonic)
SMILES O=C1N(C2=C(C)C=CC=C2C)C3=NC4=CC=CC=C4N3C5=NC(NC6=CC=C(N7CCN(C)CC7)C=C6)=NC=C15
Molecular Weight (g/mol) 530.62
Formula Weight 530.62
Percent Purity 98.2%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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