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LARP1 Rabbit anti-Drosophila, Human, Mouse, Rat, Polyclonal, Proteintech
Shop All Proteintech ProductsDescription
RNA-binding protein that promotes translation of specific classes of mRNAs downstream of the mTORC1 complex. Associates with the mRNA 5′cap in an MTOR-dependent manner and associates with mRNAs containing a 5′ terminal oligopyrimidine (5′TOP) motif, which is present in mRNAs encoding for ribosomal proteins and several components of the translation machinery. Associates with actively translating ribosomes via interaction with PABPC1/PABP and stimulates translation of mRNAs containing a 5′TOP, thereby regulating cell growth and proliferation. Positively regulates the replication of dengue virus (DENV).
Specifications
Specifications
| Antigen | LARP1 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot |
| Classification | Polyclonal |
| Concentration | 0.51 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | LARP1 |
| Gene Accession No. | Q6PKG0, Q6ZQ58 |
| Gene Alias | KIAA0731, La related protein 1, LARP, LARP1 |
| Gene Symbols | larp, Larp1 |
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