Invitrogen™ LARGE Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578393

Product Code. 15958896

Description

Positive Control: mouse liver Predicted Reactivity: Human (100%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The LARGE gene, which is one of the largest in the human genome, encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. Mutations in this gene cause MDC1D, a novel form of congenital muscular dystrophy with severe mental retardation and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Specifications

• Antigen: LARGE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Large1
• Gene Alias: Acetylglucosaminyltransferase-like 1A; acetylglucosaminyltransferase-like protein; Beta-1,3-glucuronyltransferase LARGE; BPFD#36; enr; eosinophil granule major basic protein 1; fg; froggy; glycosyltransferase-like 1A; Glycosyltransferase-like protein; glycosyltransferase-like protein LARGE1; glycosyltransferase-like protein LARGE1; LARGE xylosyl- and glucuronyltransferase 1; Gyltl1a; KIAA0609; large; LARGE xylosyl- and glucuronyltransferase 1; Large1; like-acetylglucosaminyltransferase; like-glycosyltransferase; MBP1; Mbp-1; MDC1D; MDDGA6; MDDGB6; mKIAA0609; myd; myodystrophy; prepro major basic protein 1; Xylosyltransferase LARGE
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16795, 361368, 9215
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O95461, Q9Z1M7
• Gene Symbols: Large1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LARGE. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG