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Thermo Scientific™ LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

Product Code. 10206313
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25 μg
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10206313 25 μg Each
10368273 1 mg Each
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For Research Use Only. All usage must comply with product instructions.
 
Product Code. 10206313 Supplier Thermo Scientific™ Supplier No. PV4813

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This item is not returnable. View return policy
For Research Use Only. All usage must comply with product instructions.
 

LanthaScreen™ Tb-pMAP2K1 (pSer217/221) Antibody Kit

A member of the MAP Kinase family, MAP2K1 (mitogen-activated protein kinase kinase 1) is phosphorylated at Ser217/221 by a range of MAPK family members including Raf and B-Raf. For use in combination with the Fluorescein-MAP2K1 physiological protein substrate (PV4812) to evaluate inhibitors in medium to high throughput screening applications.
TRUSTED_SUSTAINABILITY

Specifications

Applications Kinase Assay, Enzyme and Protein Activity Assays, Kinase Assay
Conjugate Tb (Terbium)/FITC/Lanthanide Chelates
Gene Alias COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, CRAF,NS5,Raf-1,c-Ra, MEKK9,MLK1,PRKE, COT,EST,ESTF,FLJ10486,MEKK8,TPL2,Tpl-2,c-CO, MEKK7,TAK1,TGF1, MEKK9,MLK1,PRKE, ASK1,MAPKKK5,MEKK, MEKK10,MLK2,MS, MEKK11,MGC17114,MLK-3,MLK3,PTK1,SPR, CRAF,NS5,Raf-1,c-Ra,
Molecular Weight of Antigen 150kDa
Quantity 25 μg
Regulatory Status RUO
Research Discipline Target and Lead Identification and Validation
Primary or Secondary Primary
Gene ID (Entrez) 10454, 10746, 1326, 4215, 4217, 4293, 4294, 4296, 5894, 673, 6885
Packaging 1 Kit(s)
Includes 0.02% Sodium azide
Content And Storage Terbium-labeled anti-MAP2K1 [pSer217/221] antibody in HEPES buffered saline. Store at -20°C.
Antibody Molecular Weight 150000 Da
Assay Entry Biochemical terbium phospho-specific activity
Format 384-well Plate
Excitation/Emission 340⁄490, 520
Reactivity Human
Shipping Condition Dry Ice
Readout End Point
Reactivity abrv Hu
Target Entry MAP3K2, RAF1 (cRAF) Y340D Y341D, MAP3K10, MAP3K9, MAP3K7/MAP3K7IP1, MAP3K5, MAP3K11, BRAF V599E, BRAF, MAP3K8, MAP3K3
Target Enzyme Serine⁄Threonine Kinases
Technique TR-FRET
Validated Kinases BRAF, MAP3K2, MAP3K3, MAP3K5, MAP3K7, MAP3K8, MAP3K9, MAP3K10, MAP3K11
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For Research Use Only. Not for use in diagnostic procedures.

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