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Invitrogen™ Langerin Polyclonal Antibody
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Product Code. 16349384
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Quantity:
100 μL
Unit Size:
100µL
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16349384 100 μL 100µL
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Product Code. 16349384 Supplier Invitrogen™ Supplier No. PA582422

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VKTNVQLLKG RVDNISTLDS EIKKNSDGME AAGVQIQMVN ESLGYVRSQF LKLKTSVEKA NAEIQILTRS WEEVSTLNAQ IPELKSDLEK ASALNTKIRA LQGSLENMSK LLKRQNDILQ VVSQGWKYFK GNFYYFSLIP Highest antigen sequence indentity to the following orthologs: Mouse - 61%, Rat - 57%.

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Langerin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CD207
Gene Accession No. Q9UJ71
Gene Alias CD 207 antigen; CD207; CD207 antigen; CD207 antigen, langerin; CD207 molecule; CD207 molecule, langerin; CLEC4K; C-type lectin domain family 4 member K; C-type lectin domain family 4, member K; Langerhans cell specific c-type lectin; langerin; RGD1565913
Gene Symbols CD207
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CD207. Recombinant protein control fragment (Product #RP-90133).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 50489
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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