Invitrogen™ LANCL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531080

Product Code. 13415597

Description

Recommended positive controls: HeLa. Predicted reactivity: Mouse (91%), Rat (91%), Chicken (84%), Rhesus Monkey (99%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.

Specifications

• Antigen: LANCL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LANCL1
• Gene Alias: 40 kDa erythrocyte membrane protein; AW124738; G protein-coupled receptor 69; G protein-coupled receptor 69A; Glutathione S-transferase LANCL1; Gpr69; Gpr69a; LanC (bacterial lantibiotic synthetase component C)-like 1; LanC (bacterial lantibiotic synthetase component); LanC lantibiotic synthetase component C-like 1; LanC lantibiotic synthetase component C-like 1 (bacterial); LanC like 1; LANCL1; LanC-like 1; LanC-like 1(bacterial); lanC-like protein 1; p40
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10314
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O43813
• Gene Symbols: LANCL1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LANCL1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG