Invitrogen™ Laminin gamma-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA537448

Product Code. 15544401

Description

This antibody detects endogenous protein at a molecular weight of 172 kDa. Purity is >95% by SDS-PAGE.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

Specifications

• Antigen: Laminin gamma-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMC3
• Gene Alias: AI562206; AW240805; Lamc3; laminin gamma 3; Laminin gamma3; laminin subunit gamma 3; laminin subunit gamma-3; laminin, gamma 3; laminin-12 subunit gamma; Laminin-14 subunit gamma; laminin-15 subunit gamma; OCCM
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10319, 23928, 311862
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9R0B6, Q9Y6N6
• Gene Symbols: LAMC3
• Immunogen: Synthetic peptide corresponding to amino acids 1355-1399 of human Laminin gamma-3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG