Laminin beta-1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA5121243

Product Code. 17712644

Description

Positive test controls include: SW480, HepG2, HT-1080, SKOV3, Mouse heart. The target is usually found in the following locations: Secreted, basement membrane, extracellular matrix, extracellular space. Immunogen sequence: EAKLRADEAK QSAEDILLKT NATKEKMDKS NEELRNLIKQ IRNFLTQDSA DLDSIEAVAN EVLKMEMPST PQQLQNLTED IRERVESLSQ VEVILQHSAA DIARAEMLLE EAKRASKSAT DVKVTADMVK EALEEAEKAQ VAAEKAIKQA DEDIQGTQNL LTSIESETAA SEETLFNASQ RISELERNVE ELKRKAAQNS GEAEYIEKVV YTVKQSAEDV KKTLDGELDE KYKKVENLIA KKTEESADAR RKAEMLQNEA KTLLAQANSK LQLLKDLERK YEDNQRYLED KAQELARLEG EVRSLLKDIS QKVAVYSTCL

Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.

Specifications

• Antigen: Laminin beta-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMB1
• Gene Alias: C77966; C80098; C81607; CLM; D130003D08Rik; I79_017505; LAMB1; Lamb-1; LAMB1; basement membrane protein; Lamb1-1; laminin B1; laminin B1 chain; laminin B1 subunit 1; laminin beta 1; laminin beta-1 chain; laminin subunit beta 1; laminin subunit beta-1; laminin, beta 1; laminin-1 subunit beta; Laminin-10 subunit beta; laminin-12 subunit beta; Laminin-2 subunit beta; laminin-6 subunit beta; Laminin-8 subunit beta; LIS5; LOW QUALITY PROTEIN: laminin subunit beta-1; MGC142015
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16777, 298941, 3912
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 0.52 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P02469, P07942
• Gene Symbols: LAMB1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1467-1786 of human Laminin beta 1 (NP_002282.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG