Invitrogen™ Laminin alpha-5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100745

Product Code. 16687224

Descrizione

Antibody detects endogenous levels of total LAMA5.

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Specifica

• Antigen: Laminin alpha-5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMA5
• Gene Alias: [a]5; AA408760; AA408762; AI853660; KIAA0533; KIAA1907; LAMA5; laminin alpha-5 chain; laminin subunit alpha 5; laminin subunit alpha-5; laminin, alpha 5; laminin-10 subunit alpha; Laminin-11 subunit alpha; laminin-15 subunit alpha; laminin-511; mKIAA0533; RP11-157P1.6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16776, 3911
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O15230, Q61001
• Gene Symbols: LAMA5
• Immunogen: A synthesized peptide derived from human LAMA5(Accession O15230), corresponding to amino acid residues V512-C562.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG