Invitrogen™ Laminin-213 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5114757

Product Code. 17227523

Description

Antibody detects endogenous levels of total LAMC3.

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

Specifications

• Antigen: Laminin-213
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LAMC3
• Gene Alias: AI562206; AW240805; Lamc3; laminin gamma 3; Laminin gamma3; laminin subunit gamma 3; laminin subunit gamma-3; laminin, gamma 3; laminin-12 subunit gamma; Laminin-14 subunit gamma; laminin-15 subunit gamma; OCCM
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10319
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y6N6
• Gene Symbols: LAMC3
• Immunogen: A synthesized peptide derived from human LAMC3(Accession Q9Y6N6), corresponding to amino acid residues V497-L547.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG