Lamin A/C Mouse, Clone: 4A7, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9688-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionThe monoclonal antibody 4A7 recognizes human, mouse, rabbit and hamster lamin A/C. Lamins are nuclear intermediate filament proteins that provide framework for the nuclear envelope, maintain cell morphology, and protect the nucleus from mechanical, thermal, and oxidative stresses. Lamins also play a role in nuclear assembly, chromatin organization, DNA replication, RNA transcription, cell signaling, and apoptosis. Lamin C is a splice variant of Lamin A and both are A-type lamins. Lamin A and C are crucial for skeletal and cardiac development and function. Defects in A-type lamins result in cardiomyopathy, muscular dystrophy, peripheral neuropathy, lipodystrophy, restrictive dermopathy, and progeroid disorders.
|Store at 2-8°C.|
|ELISAþImmunocytochemistryþImmunohistochemistry (Frozen)þMicroscopyþWestern Blot|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
For Research Use Only.