Lambda Light Chain Antibody (LcN-2 + ICO-106), Novus Biologicals™

Mouse Monoclonal Antibody

Product Code	Brand	Quantity
18185432	Novus Biologicals NBP2-34236-0.02MG	0.02 mg
18115763	Novus Biologicals NBP2-34236-0.1MG	0.1 mg

Description

Lambda Light Chain Monoclonal specifically detects Lambda Light Chain in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Lambda Light Chain
• Dilution: Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: IGLC, immunoglobulin lambda constant group
• Gene Symbols: IGL
• Isotype: IgG1, IgG2a κ
• Purification Method: Protein A purified
• Test Specificity: This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

• Clone: LcN-2 + ICO-106
• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P01701
• Gene ID (Entrez): 3536
• Immunogen: Purified human IgG (LcN-2 and ICO-106)
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.
• Molecular Weight of Antigen: 22.5 kDa