LAG-3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16876284	Proteintech 16616-1-AP-20UL	20 μL
16866284	Proteintech 16616-1-AP-150UL	150 μL

Description

NEK9, a NEK type protein kinase, regulates chromosome alignment and segregation in mitosis. The protein has a N-terminal NIMA-like catalytic domain, a central domain with homology to the guanine nucleotide exchange factor for the GTPase Ran (RCC1), and a C-terminal coiled-coil domain. It is phosphorylated by active p34(Cdc2) and is capable of autophosphorylation and oligomerization. The activated protein binds Nek6 and RCC1, and has been shown to associate with the human homolog of the Drosophila protein Bicaudal D (Bicd2) in vivo and to phosphorylate this coiled-coil protein in vitro. NEK9 expression has been documented in normal human brain. ESTs have been isolated from several tissue libraries, including normal bone, lymph and thymus and cancerous cervix, eye, lymph and placenta.

Specifications

• Antigen: LAG-3
• Applications: Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse, Human, Rat
• Gene Accession No.: P18627, Q5BK54, Q61790
• Gene ID (Entrez): 16768, 297596, 3902
• Immunogen: LAG-3 Fusion Protein Ag9909
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: LAG3

• Concentration: 0.15 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: CD223, FDC, LAG3, LAG-3, lymphocyte activation gene 3, Protein FDC
• Gene Symbols: Lag3
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody