Invitrogen™ LACC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559081

Product Code. 15706951

Description

Immunogen sequence: FGLKLNSQKN CHQTLLKTLN AVQYHHAAKA KFLCIMCCSN ISYERDGEQD NCEIETSNGL SALLEEFEIV SCPSMAATLY TIKQKIDEKN LSSIKVI Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 59%.

This gene encodes an oxidoreductase that promotes fatty-acid oxidation, with concomitant inflammasome activation, mitochondrial and NADPH-oxidase-dependent reactive oxygen species production, and bactericidal activity of macrophages. The encoded protein forms a complex with fatty acid synthase on peroxisomes and is thought to be modulated by peroxisome proliferator-activated receptor signaling events. Naturally occurring mutations in this gene are associated with inflammatory bowel disease, Behcet's disease, leprosy, ulcerative colitis, early-onset Crohn's disease, and systemic juvenile idiopathic arthritis.

Specifications

• Antigen: LACC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LACC1
• Gene Alias: 9030625A04Rik; C12H13orf31; C13orf31; FAMIN; Fatty acid metabolism-immunity nexus; LACC1; laccase (multicopper oxidoreductase) domain containing 1; laccase domain containing 1; laccase domain-containing protein 1; purine nucleoside phosphorylase LACC1; laccase domain-containing protein 1; RGD1310185; si:ch211-187f22.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 144811
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IV20
• Gene Symbols: LACC1
• Immunogen: Recombinant protein corresponding to Human LACC1. Recombinant protein control fragment (Product #RP-98003).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG