Transglutaminase II Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ Transglutaminase II Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Brand:  Epredia MS-224-B

Product Code. 12610597

Description

Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.

Host Species: Mouse

Clone: CUB 7402

Isotype: IgG1/κ

Species Reactivity: Human, Dog, Rabbit and Guinea Pig. Does not react with mouse and rat. Others not known.

Epitope: aa 447-478

Immunogen: Purified guinea pig liver TGase II

Molecular Weight: 77-85kDa

Positive Control: HUVEC cells, Breast CA

Cellular Localization: Cytoplasm, membrane and extracellular matrix Ab-1 inhibits the TGase II activity.

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native and denatured)
• Affinity Purification
• Biological Blockade

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Transglutaminase II Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Neuroscience
• Target Species: Canine, Guinea Pig, Human, Rabbit
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: CUB 7402
• Conjugate: Biotin
• Immunogen: Purified guinea pig liver TGase II
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated