TIMP-1 Ab-2 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ TIMP-1 Ab-2, Mouse Monoclonal Antibody.

Brand:  Epredia MS-608-P1ABX

Product Code. 12601747

Description

Tissue inhibitor of metalloproteinases-1 (TIMP-1) and Tissue inhibitor of metalloproteinases-2 (TIMP-2) are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-1 forms a complex of 1:1 stoichiometry with activated interstitial collagenase, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A), and latent and active forms 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Host Species: Mouse

Clone: 102D1

Isotype: IgG1

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: Recombinant human TIMP-1

Molecular Weight: 28.5kDa

Positive Control: Conditioned, serum-free medium from (TPA-treated) human fetal lung cell line HFL-1; Bladder, breast and ovarian CA

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: TIMP-1 Ab-2
• Classification: Monoclonal
• Concentration: 1mg/mL
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Proteases And Inhibitors
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 102D1
• Conjugate: Unconjugated
• Immunogen: Recombinant human TIMP-1
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated