Epredia™ Lab Vision™ Paxillin Ab-1 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide

Provide accurate, reproducible results with the Epredia™ Paxillin Ab-1, Mouse Monoclonal Antibody.

Brand:  Epredia™ MS-404-P1

Product Code. 12611357

Description

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.

Host Species: Mouse

Clone: 5H11

Isotype: IgG1/κ

Species Reactivity: Human and Rat. Others not known.

Epitope: Not determined

Immunogen: Purified recombinant full-length human paxillin protein

Molecular Weight: 68kDa

Positive Control: HeLa cells, Colon CA

Cellular Localization: Membrane and cytoplasmic

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunofluorescence
• Immunoprecipitation (Native verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Paxillin Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Cytoskeletal Protein
• Target Species: Human, Rat
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 5H11
• Conjugate: Unconjugated
• Immunogen: Purified recombinant full-length human paxillin protein
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated