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Epredia™ Lab Vision™ PARP (Poly ADP-Ribose Polymerase) Ab-2 Rabbit Polyclonal Antibody with BSA and azide
Shop All Epredia ProductsDescription
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
Host Species: Rabbit
Isotype: IgG
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: N-terminal
Immunogen: A synthetic peptide for the N-terminal region of human PARP
Molecular Weight: 116kDa
Positive Control: Raji cells, Tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin only)
- Western Blotting
Note:
USA: RUO; Int'l: RUO
Specifications
Specifications
| Antigen | PARP (Poly ADP-Ribose Polymerase) Ab-2 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1mg/mL |
| Conjugate | Unconjugated |
| Host Species | Rabbit |
| Immunogen | A synthetic peptide for the N-terminal region of human PARP |
| Purification Method | Purified with BSA and Azide |
| Quantity | 100 μL |
| Regulatory Status | RUO |
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