Epredia™ Lab Vision™ PARP (Poly ADP-Ribose Polymerase) Ab-2 Rabbit Polyclonal Antibody with BSA and azide

Deliver accurate, reproducible results with the Epredia™ PARP (Poly ADP-Ribose Polymerase) Ab-2, Rabbit Polyclonal Antibody.

Brand:  Epredia™ RB-1516-P0

Product Code. 12662977

Description

Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse and Rat. Others not known.

Epitope: N-terminal

Immunogen: A synthetic peptide for the N-terminal region of human PARP

Molecular Weight: 116kDa

Positive Control: Raji cells, Tonsil

Cellular Localization: Nuclear

Recommended for:

• Immunohistochemistry (Formalin/paraffin only)
• Western Blotting

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: PARP (Poly ADP-Ribose Polymerase) Ab-2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Immunogen: A synthetic peptide for the N-terminal region of human PARP
• Quantity: 100 μL
• Research Discipline: Apoptosis
• Target Species: Human, Mouse
• Isotype: IgG

• Applications: Western Blot
• Concentration: 1mg/mL
• Host Species: Rabbit
• Purification Method: Purified with BSA and Azide
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated