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Description
Alpha methylacyl-CoA-racemase (AMACR), also known as p504s is an enzyme involved in the metabolism of branched-chain fatty acids. p504s is expressed in various normal tissues and carcinomas, while it is overexpressed over 30-fold in prostate carcinoma compared to benign glandular tissues1. When p504s is overexpressed in atypical glands without basal cells, it establishes a diagnosis of prostatic carcinoma. High-grade prostatic intraepithelial neoplasia, atypical adenomatous hyperplasia and urothelial carcinoma may also express p504s.
Host Species: Rabbit
Clone: 13H4
Isotype: IgG
Species Reactivity: Human. Others not tested.
Immunogen: Human p504s/AMACR polypeptide
Molecular Weight: ∽45 kDa
Positive Control: Prostate carcinoma
Cellular Localization: Cytoplasmic
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Specifications
Specifications
| Antigen | p504s/AMACR |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Clone | 13H4 |
| Conjugate | Unconjugated |
| Host Species | Rabbit |
| Immunogen | Human p504s/AMACR polypeptide |
| Quantity | 1 mL |
| Regulatory Status | ASR |
| Research Discipline | Cancer and Tumor Biology |
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Product Title
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