MMP-3 (Stromelysin-1) Ab-1 Mouse Monoclonal Antibody, Epredia™

Epredia™ MMP-3 (Stromelysin-1) Ab-1, Mouse Monoclonal Antibody provides accurate, reproducible results.

Marca:  Epredia MS-809-P1

Codice prodotto. 12642367

Descrizione

Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs) are implicated in the invasive potential of malignant tumors. Stromelysin (MMP3/Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens.

Host Species: Mouse

Clone: SL-1 ID3

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Not determined

Immunogen: APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)

Molecular Weight: 54/59kDa (proform) and 44/49kDa (active form)

Positive Control: Conditioned, serum-free medium from TPA-treated human endometrial cells

Cellular Localization: Cytoplasmic

Recommended for:

• Immunohistochemistry (Not Suitable)
• Western Blotting
• Immunofluorescence

Note:

USA: RUO; Int'l: RUO

Specifica

• Antigen: MMP-3 (Stromelysin-1) Ab-1
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 500 μL
• Research Discipline: Proteases And Inhibitors
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Western Blot
• Clone: SL-1 ID3
• Conjugate: Unconjugated
• Immunogen: APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1 (SL-1)
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated