IGF-1R (α-subunit) Ab-1 Mouse Monoclonal Antibody, Epredia™

Provide accurate, reproducible results with the Epredia™ IGF-1R (α-Subunit) Ab-1, Mouse Monoclonal Antibody.

Product Code	Brand	Quantity	Conjugate	Concentration
12651877	Epredia MS-641-B0	100 μL	Biotin	200μg/mL
12661877	Epredia MS-641-B1	500 μL	Biotin	200μg/mL
12641877	Epredia MS-641-B	1 mL	Biotin	200μg/mL
12681877	Epredia MS-641-P0	100 μL	Unconjugated	200μg/mL
12691877	Epredia MS-641-P1	500 μL	Unconjugated	200μg/mL
12671877	Epredia MS-641-P	1 mL	Unconjugated	200μg/mL
12601887	Epredia MS-641-P1ABX	100 μL	Unconjugated	1mg/mL
12611887	Epredia MS-641-PABX	200 μL	Unconjugated	1mg/mL

Description

IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of α- and Β-subunits, which are disulfide-linked in a Β-α-α-Β configuration in the mature receptor. The α-subunit is completely extracellular, while the Β-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.

Host Species: Mouse

Clone: 24-31

Isotype: IgG1

Species Reactivity: Human. Weakly reacts with Rabbit. Does not react with rat. Pig unknown.

Epitope: aa 283-440 (exon 4-6)

Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA

Molecular Weight: 125kDa

Positive Control: Placenta or Breast CA

Cellular Localization: Membrane

Recommended for:

• Western Blotting (Not suitable)
• Immunoprecipitation
• ELISA
• Acts as a Weak IGF-like Agonist in Bioassays (Thymidine incorporation into DNA)
• Does Not Significantly Inhibit IGF-1 Binding

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: IGF-1R (alpha-Subunit) Ab-1
• Applications: Immunoprecipitation
• Form: Concentrated
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1

• Clone: 24-31
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Neuroscience
• Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA
• Primary or Secondary: Primary