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Epredia™ Lab Vision™ Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4 Mouse Monoclonal Antibody, 200μg/mL, BSA and azide
Obtain accurate, reproducible results in immunohistochemistry, immunofluorescence and immunoprecipitation experiments.
£132.60 - £652.80
Specifications
| Antigen | Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4 |
|---|---|
| Clone | M3A7 |
| Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Form | Concentration | Price | Quantity & Availability | |||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Form | Concentration | Price | Quantity & Availability | |||
|
12619376
|
Epredia™
MS-1249-P0 |
100 μL | Concentrated | 200μg/mL | |||||
|
12629376
|
Epredia™
MS-1249-P1ABX |
100 μL | Concentrated | 1mg/mL | |||||
|
12639376
|
Epredia™
MS-1249-PABX |
200 μL | Concentrated | 1mg/mL | |||||
|
12609376
|
Epredia™
MS-1249-P1 |
500 μL | Concentrated | 200μg/mL | |||||
|
12699366
|
Epredia™
MS-1249-P |
1 mL | Concentrated | 200μg/mL | |||||
|
12679376
|
Epredia™
MS-1249-R7 |
7 mL | Prediluted | Prediluted | |||||
Description
CFTR (cystic fibrosis transmembrane conductance regulator) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Host Species: Mouse
Clone: M3A7
Isotype: IgG1
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: aa 1370-1380
Immunogen: Recombinant protein encoding NBF2 domain of human CFTR
Molecular Weight: 165-170 kDa
Positive Control: Pancreas
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting (Not verified)
- Immunofluorescence
- Immunoprecipitation
Note:
USA: RUO; Int'l: RUO
Specifications
| Cystic Fibrosis Transmembrane Regulator (CFTR) Ab-4 | |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| Unconjugated | |
| RUO | |
| Recombinant protein encoding NBF2 domain of human CFTR | |
| Primary |
| M3A7 | |
| Monoclonal | |
| Mouse | |
| Human, Mouse, Rat | |
| IgG1 |
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