CD47 Ab-2 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunofluorescence, immunoprecipitation and flow cytometry experiments with Epredia™ CD47 Ab-2, Mouse Monoclonal Antibody.

Brand:  Epredia MS-1302-P

Product Code. 12649526

Description

CD47 antigen, also known as integrin associated-protein (IAP), is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. CD47 may play a role as a signal transducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Host Species: Mouse

Clone: B6H12.2

Isotype: IgG1/κ

Species Reactivity: Human. Others not known.

Epitope: Ig domain

Immunogen: Intact CD47 purified from placenta

Molecular Weight: 47-52 kDa (reduced) and 45-50.5, 110 kDa (nonreduced)

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunofluorescence (Methanol fixed only)
• Immunoprecipitation (Native only)
• Flow Cytometry
• Blocks binding of SIRPα
• Inhibits in assays in which CD47-integrin association is required

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: CD47 Ab-2
• Classification: Monoclonal
• Concentration: 200μg/mL
• Host Species: Mouse
• Quantity: 1 mL
• Research Discipline: Hematopoietic
• Target Species: Human
• Isotype: IgG2a κ

• Applications: Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: B6H12.2
• Conjugate: Unconjugated
• Immunogen: Intact CD47 purified from placenta
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated