Epredia™ Lab Vision™ CD45RA Ab-3 Mouse Monoclonal Antibody, 1mL; 200μg/mL, BSA and azide

Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD45RA Ab-3, Mouse Monoclonal Antibody.

Product Code	Brand	Form	Quantity
12610277	Epredia™ MS-1845-P	Concentrated	1 mL

Description

CD45 or Leukocyte Common Antigen (LCA/T200) belongs to a family of membrane sialoglycoproteins with MW of 180kDa-220 kDa. Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates various isoforms. CD45RA.is a single chain glycoprotein. It is expressed on appoximately 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. CD45RA are naive or virgin T-cells while, T-cells expressing CD45RO are memory T-cells.

Host Species: Mouse

Clone: 4KB5

Isotype: IgG1/κ

Species Reactivity: Human. Others not tested

Epitope: Not determined

Immunogen: Hairy cell leukemia cells

Molecular Weight: 205-220 kDa

Positive Control: Lymph node or tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)

Specifications

• Antigen: CD45RA Ab-3
• Applications: Immunohistochemistry (Paraffin)
• Conjugate: Unconjugated
• Regulatory Status: IVD
• Target Species: Human
• Isotype: IgG2a κ

• Clone: 4KB5
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Oncogenesis
• Immunogen: Hairy cell leukemia cells
• Primary or Secondary: Primary