L1CAM Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 20659-1-AP-20UL

Product Code. 16810235

Description

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.

Specifications

• Antigen: L1CAM
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: L1CAM
• Gene Alias: CAML1, CD171, HSAS, HSAS1, L1 cell adhesion molecule, L1CAM, MASA, MIC5, N CAM L1, N CAML1, NCAM L1, S10, SPG1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16728, 3897, 50687
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P11627, P32004, Q05695
• Gene Symbols: L1cam
• Immunogen: Peptide
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat, Mouse
• Product Type: Antibody
• Isotype: IgG