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L-Buthionine-(S,R)-sulfoximine, MedChemExpress

Product Code. 16490437
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Product Code. 16490437 Supplier Medchem Express Supplier No. HY106376A

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Description

MedChemExpress L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

L-Buthionine-(S,R)-sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.

Specifications

Chemical Name or Material L-Buthionine-(S,R)-sulfoximine
Physical Form Solid
CAS 83730-53-4
Color Off-White
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C8H18N2O3S
For Use With (Application) Cancer-programmed cell death
Synonym L-Buthionine sulfoximine L-BSO
Solubility Information H2O : 18.33 mg/mL (82.45 mM; Need ultrasonic) ∣DMSO : < 1 mg/mL (ultrasonic) (insoluble or slightly soluble)
SMILES N[C@H](C(O)=O)CCS(CCCC)(=O)=N
Molecular Weight (g/mol) 222.31
Formula Weight 222.31
Percent Purity 95.0%
Grade Research
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