L(+)-Amethopterin hydrate, 99%, ACROS Organics™

Brand:  Acros Organics 208100250

Product Code. 10002690

Chemical Identifiers

• CAS: 133073-73-1
• Molecular Weight (g/mol): 454.44
• InChI Key: TXQDMGIRZSHAQM-GXKRWWSZSA-N
• PubChem CID: 45157423
• SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O.O.O

• Molecular Formula: C₂₀H₂₂N₈O₅·xH₂O
• MDL Number: MFCD00150847
• Synonym: l +-amethopterin dihydrate, methotrexate dihydrate, dihydrate methotrexate, 2s-2-4-2,4-diaminopteridin-6-yl methyl methylamino phenyl carbonylamino pentanedioic acid, hydrate, hydrate
• IUPAC Name: (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;dihydrate

Specifications

• Chemical Name or Material: L(+)-Amethopterin hydrate
• Packaging: Glass Bottle
• Water: 13% max. (K.F.)
• Melting Point: 195°C
• CAS: 133073-73-1
• Molecular Formula: C₂₀H₂₂N₈O₅·xH₂O
• Merck Index: 14, 5985
• Solubility Information: Solubility in water: insoluble in water. Other solubilities: insoluble in alcohol,chloroform,ether,slightly soluble in dilute hydrochloric acid,soluble in dilute solutions of alkali hydroxides a
• SMILES: CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O.O.O
• Molecular Weight (g/mol): 454.44
• Formula Weight: 454.44
• Percent Purity: 99%

• Infrared Spectrum: Authentic
• Specific Rotation: + 21.5
• Color: Yellow to Orange
• Quantity: 25mg
• Assay Percent Range: 98.5% min. (HPLC)
• MDL Number: MFCD00150847
• Synonym: l +-amethopterin dihydrate, methotrexate dihydrate, dihydrate methotrexate, 2s-2-4-2,4-diaminopteridin-6-yl methyl methylamino phenyl carbonylamino pentanedioic acid, hydrate, hydrate
• InChI Key: TXQDMGIRZSHAQM-GXKRWWSZSA-N
• IUPAC Name: (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;dihydrate
• PubChem CID: 45157423
• Physical Form: Crystalline Powder

Safety and Handling

Product Identifier

• L(+)-Amethopterin hydrate

Signal Word

• Danger

Hazard Category

• Acute toxicity Category 3
• Germ cell mutagenicity Category 1B
• Reproductive toxicity Category 1A

Hazard Statement

• H360D-May damage the unborn child.
• H340-May cause genetic defects.
• H301-Toxic if swallowed.

Precautionary Statement

• P201-Obtain special instructions before use.
• P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
• P308+P313-IF exposed or concerned: Get medical advice/attention.