Invitrogen™ KV4.1 (KCND1) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA537457

Product Code. 15584401

Description

This antibody detects endogenous protein at a molecular weight of 71 kDa. Purity is >95% by SDS-PAGE.

The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.

Specifications

• Antigen: KV4.1 (KCND1)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Kcnd1
• Gene Alias: 1110037K09Rik; Kca2-1; Kcnd1; KV4.1; mShal; mShal1; potassium channel, voltage gated Shal related subfamily D, member 1; potassium channel, voltage gated Shal-related subfamily D, member 1; potassium voltage gated channel Shal-related family member 1; potassium voltage gated channel, Shal-related family, member 1; potassium voltage-gated channel subfamily D member 1; potassium voltage-gated channel, Shal-related family, member 1; potassium voltage-gated channel, Shal-related subfamily, member 1; Shal; Shal1; Shal-type potassium channel; Voltage-gated potassium channel subunit Kv4.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16506, 3750
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q03719, Q9NSA2
• Gene Symbols: Kcnd1
• Immunogen: Synthetic peptide corresponding to amino acids 559-610 of human KV41.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG