KV3.2 (KCNC2) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Marca:  Invitrogen PA577579

Codice prodotto. 15944085

Descrizione

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.

Specifica

• Antigen: KV3.2 (KCNC2)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNC2
• Gene Alias: Kcnc2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 246153, 268345, 3747
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 1% BSA, 5% sucrose and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P22462, Q14B80, Q96PR1
• Gene Symbols: Kcnc2
• Immunogen: Peptide DLGGKRLGIEDAAGLGGPDGK(C), corresponding to amino acid residues 184-204 of rat KV 3.2
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG