KV3.2 (KCNC2) Polyclonal Antibody, Invitrogen™

Product Code.	Quantity	unitSize
15944085	50 μL	50µL

Product Code. 15944085 Supplier Invitrogen Supplier No. PA577579

Description

Rabbit Polyclonal Antibody

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels. The subunits vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha subunits, which include the KV1, KV2, KV3, KV4 and KV9 proteins, as well as accessory subunits that modify the gating properties of the coexpressed KV subunits. KV3.2 is a multipass membrane protein that regulates the voltage-dependent K+ permeability of excitable membranes. The tail of KV3.2 may be influential in the targeting of the channel to specific subcellular compartments and/or the regulation of channel activity.

Specifications

• Antigen: KV3.2 (KCNC2)
• Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.3 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 5% sucrose and 0.05% sodium azide; pH 7.4
• Gene: KCNC2
• Gene Accession No.: P22462, Q14B80, Q96PR1
• Gene Alias: Kcnc2
• Gene Symbols: Kcnc2
• Host Species: Rabbit
• Immunogen: Peptide DLGGKRLGIEDAAGLGGPDGK(C), corresponding to amino acid residues 184-204 of rat KV 3.2
• Purification Method: Antigen affinity chromatography
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 246153, 268345, 3747
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG