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KV1.8 (KCNA10) Polyclonal Antibody, Invitrogen™
Description
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 μL of deionized water.
KCNA10 is a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
Specifications
Specifications
| Antigen | KV1.8 (KCNA10) |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.8 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA and 0.05% sodium azide; pH 7.4 |
| Gene | KCNA10 |
| Gene Accession No. | B2RQA1, Q16322 |
| Gene Alias | KV1.8 |
| Gene Symbols | Kcna10 |
| Show More |
Product Title
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