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Tocris Bioscience™ KU 55933

Description
Potent, selective and competitive ATM kinase inhibitor (Ki = 2.2 nM, IC50 values are 13, 2500, 9300, 16600, > 100000 and > 100000 nM at ATM, DNA-PK, mTOR, PI 3-kinase, PI 4-K and ATR respectively). Decreases viability of MCF-7, A549 and HCT116 cells and decreases p21CIP1 levels in vitro. Acts as a radio- and chemosensitizer for the treatment of cancer.
Specifications
Specifications
| CAS | 587871-26-9 |
| Quantity | 10 mg |
| Molecular Formula | C21H17NO3S2 |
| Formula Weight | 395.49 |
| Purity | >98% |
| Molecular Weight (g/mol) | 395.49 |
| Chemical Name or Material | KU 55933 |
Product Title
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