Invitrogen™ KTN1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA588557

Product Code. 16566761

Description

Immunogen sequence: MEFYESAYFI VLIPSIVITV IFLFFWLFMK ETLYDEVLAK QKREQKLIPT KTDKKKAEKK KNKKKEIQNG NLHESDSESV PRDFKLSDAL AVEDDQVAPV; Positive Samples: K-562, SKOV3, Raji, HeLa, HT-1080, Mouse heart, Rat testis; Cellular Location: Endoplasmic reticulum membrane, Single-pass type II membrane protein.

Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.

Specifications

• Antigen: KTN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KTN1
• Gene Alias: CG1; CG-1 antigen; KIAA0004; Kinectin; kinectin 1; kinectin 1 (kinesin receptor); kinesin receptor; KNT; ktn1; MU-RMS-40.19
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16709, 361029, 3895
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q61595, Q86UP2
• Gene Symbols: KTN1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KTN1 (NP_0010729891).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG