Invitrogen™ KSV Cyclin D Monoclonal Antibody (94B)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA191431

Product Code. 11521192

Description

MA1-91431 detects D type cyclin from virus samples.

This protein was identified by the interaction with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein was shown to interact with Cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.

Specifications

• Antigen: KSV Cyclin D
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Host Species: Rat
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 94B
• Conjugate: Unconjugated
• Gene Alias: B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; cyclin D1; D11S287E; G1/S-specific cyclin-D1; Kaposi's Sarcoma Virus Type D Cyclin; PRAD1; PRAD1 oncogene; U21B31
• Immunogen: Recombinant fusion protein produced from a clone from KSV.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid