KPNA6 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16810054	Proteintech 12366-2-AP-20UL	20 μL
16800054	Proteintech 12366-2-AP-150UL	150 μL

Description

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.

Specifications

• Antigen: KPNA6
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: O60684
• Gene ID (Entrez): 23633
• Immunogen: KPNA6 Fusion Protein Ag3040
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: KPNA6

• Concentration: 0.19 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: Importin subunit alpha 7, IPOA7, Karyopherin subunit alpha 6, KPNA6
• Gene Symbols: KPNA6
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody