KN-62, MedChemExpress

Product Code.	Quantity	unitSize
16478317	5 mg	5mg
16425628	10 mg	10mg
16411797	50 mg	50mg

Product Code. 16478317 Supplier Medchem Express Supplier No. HY13290

Description

MedChemExpress KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.

KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.

Specifications

• Chemical Name or Material: KN-62
• CAS: 127191-97-3
• Color: Yellow
• Purity Grade Notes: Research
• Molecular Formula: C₃₈H₃₅N₅O₆S₂
• Quantity: 5 mg
• Solubility Information: DMSO : ≥ 100 mg/mL (138.53 mM)
• SMILES: O=C(N1CCN(C2=CC=CC=C2)CC1)[C@H](CC3=CC=C(C=C3)OS(=O)(C4=CC=CC5=C4C=CN=C5)=O)N(C)S(=O)(C6=CC=CC7=C6C=CN=C7)=O
• Molecular Weight (g/mol): 721.84
• Formula Weight: 721.84
• Percent Purity: 98.27%
• Grade: Research
• Physical Form: Powder
• For Use With (Application): Cancer-Kinase/protease

Research purposes only