Invitrogen™ KLHL21 Monoclonal Antibody (2H4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA515654

Product Code. 11325623

Description

MA5-15654 targets KLHL21 in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15654 immunogen is purified recombinant fragment of human KLHL21 expressed in E. Coli.. MA5-15654 detects KLHL21 which has a predicted molecular weight of approximately 66kDa.

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.

Specifications

• Antigen: KLHL21
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q9UJP4
• Gene Symbols: KLHL21
• Immunogen: Purified recombinant fragment of human KLHL21 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 9903
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 2H4
• Conjugate: Unconjugated
• Gene: KLHL21
• Gene Alias: 1810045K06Rik; D330008A20; kelch like family member 21; kelch-like 21; kelch-like family member 21; kelch-like protein 21; KIAA0469; Klhl21; MGC99635; mKIAA0469; RGD1305863
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1