Invitrogen™ KLHL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA568640

Product Code. 15837053

Description

This target displays homology in the following species: Cow: 79%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%.

The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.

Specifications

• Antigen: KLHL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLHL1
• Gene Alias: FLJ30047; kelch like family member 1; kelch-l like; kelch-like 1; kelch-like family member 1; kelch-like protein 1; KIAA1490; Klhl1; Mayven-related protein 2; mKIAA1490; MRP2; RP11-394C23.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290426
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: 0
• Gene Symbols: KLHL1
• Immunogen: synthetic peptide directed towards the N-terminal region of rat KLHL1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG