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Invitrogen™ KLHL1 Polyclonal Antibody
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Product Code. 15837053
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Quantity:
100 μL
Unit Size:
100µL
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15837053 100 μL 100µL
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Product Code. 15837053 Supplier Invitrogen™ Supplier No. PA568640

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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 79%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%.

The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLHL1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene KLHL1
Gene Accession No. 0
Gene Alias FLJ30047; kelch like family member 1; kelch-l like; kelch-like 1; kelch-like family member 1; kelch-like protein 1; KIAA1490; Klhl1; Mayven-related protein 2; mKIAA1490; MRP2; RP11-394C23.1
Gene Symbols KLHL1
Host Species Rabbit
Immunogen synthetic peptide directed towards the N-terminal region of rat KLHL1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290426
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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