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Invitrogen™ KLHL1 Polyclonal Antibody

Product Code. 12818212
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12818212 100 μg 100µg
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Product Code. 12818212 Supplier Invitrogen™ Supplier No. PA519998

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-19998 can be used with blocking peptide PEP-0120.

The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLHL1
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene KLHL1
Gene Accession No. Q9NR64
Gene Alias FLJ30047; kelch like family member 1; kelch-l like; kelch-like 1; kelch-like family member 1; kelch-like protein 1; KIAA1490; Klhl1; Mayven-related protein 2; mKIAA1490; MRP2; RP11-394C23.1
Gene Symbols KLHL1
Host Species Rabbit
Immunogen A 14 amino acid peptide from near the amino-terminus of human KLHL1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 290426, 57626
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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