Invitrogen™ KLF4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520897

Product Code. 12809042

Description

A suggested positive control is human liver tissue lysate. PA5-20897 can be used with blocking peptide PEP-1011.

Kruppel like factor 4 (KLF4) protein is encoded by the KLF4 gene located on chromosome 9 in humans. It is also known as gut-enriched Kruppel-like factor (GKLF) or epithelial zinc-finger protein (EZF) and belongs to a family of conserved Kruppel-like factor family of DNA binding zinc finger transcription factors. KLF4 exerts its functional relevance across varied cellular pathways. As one of the four Yamanaka factors, it plays a key role in reprogramming differentiated cells into pluripotent stem cells. Most studies have focused on its specific role in endothelial cell signaling, adipogenesis, differentiation, embryogenesis and cell cycle control. Localization plays an important role in the biological significance of this protein wherein nuclear localization is associated with its function as an oncogene and cytosolic localization with tumor suppression specific effect.

Specifications

• Antigen: KLF4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLF4
• Gene Alias: endothelial Kruppel-like zinc finger protein; epithelial zinc finger protein EZF; Ezf; Gklf; gut Kruppel-like factor; gut-enriched krueppel-like factor; high mobility group nucleosomal binding domain 3; high mobility group nucleosome-binding domain-containing protein 3; HMGN3; KLF4; Krueppel-like factor 4; Kruppel like factor 4; Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF); Kruppel-like factor 4 (gut); PNAS-24; PNAS-25; RP11-150J11.1; thyroid hormone receptor interacting protein 7; Thyroid receptor-interacting protein 7; TR-interacting protein 7; TRIP7; Zie
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114505, 16600, 9314
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O43474, Q60793
• Gene Symbols: KLF4
• Immunogen: A 20 amino acid peptide near the carboxy terminus of human KLF4.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG