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Invitrogen™ KLF17 Polyclonal Antibody
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Product Code. 16587311
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Quantity:
100 μL
Unit Size:
100µL
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16587311 100 μL 100µL
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Product Code. 16587311 Supplier Invitrogen™ Supplier No. PA589403

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QMLPPQDAHD LGMPPAESQS LLVLGSQDSL VSQPDSQEGP FLPEQPGPAP QTVEKNSRPQ EGTGRRGSSE ARPYCCNYEN CGKAYTKRSH LVSHQRKHTG ERPYSCNWES CSWSFFRSDE LRRHMRVHTR YRPYKCDQCS REFMRSDHLK QHQKTHRPGP SDPQANNNNG EQDSPPAAGP; Positive Samples: U-87MG, HepG2, MCF7, Mouse brain; Cellular Location: Nucleus.

KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLF17
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene KLF17
Gene Accession No. Q5JT82, Q8CFA7
Gene Alias 7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; FLJ40160; germ cell specific zinc finger protein; germ cell-specific zinc finger protein; Gzf; KLF17; Krueppel-like factor 17; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZLF393; ZNF393
Gene Symbols KLF17
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 210-389 of human KLF17 (NP_7757553).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 128209, 75753
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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