Invitrogen™ KLF17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA550340

Product Code. 15614275

Description

The antibody detects endogenous levels of total KLF17 protein.

KLF17 is a transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.

Specifications

• Antigen: KLF17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KLF17
• Gene Alias: 7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; FLJ40160; germ cell specific zinc finger protein; germ cell-specific zinc finger protein; Gzf; KLF17; Krueppel-like factor 17; Kruppel like factor 17; Kruppel-like factor 17; novel zinc-finger protein; Zfp393; Zinc finger protein 393; ZLF393; ZNF393
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 128209
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q5JT82
• Gene Symbols: KLF17
• Immunogen: Fusion protein corresponding to residues near the C terminal of human Kruppel-like factor 17.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG