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Invitrogen™ KLC2 Polyclonal Antibody
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Product Code. 15707041 Shop All Thermo Scientific Products
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100 μL
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100µL
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Product Code. 15707041 Supplier Invitrogen™ Supplier No. PA559175

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Rabbit Polyclonal Antibody

Immunogen sequence: TLEDCASRNR KQGLDPASQT KVVELLKDGS GRRGDRRSSR DMAGGAGPRS ESDLEDVGPT AEWNG Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 88%.

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KLC2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KLC2
Gene Accession No. Q9H0B6
Gene Alias 8030455F02Rik; AW212649; Kinesin light chain 2; KLC 2; KLC2; KLC-2
Gene Symbols KLC2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human KLC2. Recombinant protein control fragment (Product #RP-97482).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64837
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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