Invitrogen™ KISS1R Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527180

Product Code. 13491317

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Raji. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

GCPR54 is a galanin-like G protein coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the protein suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that it appears to play a role in the onset of puberty. GPR54 has been reported in various human brain regions, placenta, pancreas, and spinal cord, and at lower levels in spleen, peripheral blood leukocytes, testis, lymph node, thymus, small intestine, stomach, lung, and kidney. The receptor is also abundant in tumor tissues. In rat, GPR54 is expressed in liver, intestine, and in the pons, midbrain, thalamus, hypothalamus, hippocampus, amygdala, cortex (including frontal), and striatum. ESTs have been isolated from normal placenta and kidney cancer libraries.

Specifications

• Antigen: KISS1R
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KISS1R
• Gene Alias: AXOR12; CPPB1; G protein-coupled receptor 54; Gpr54; G-protein coupled receptor 54; G-protein coupled receptor OT7T175; HH8; HOT7T175; Hypogonadotropin-1; kiSS-; KiSS-1; KISS1 receptor; kiSS-1 receptor; KISS1R; KiSS-1R; Kisspeptins receptor; metastin receptor; mOT7T175; orphan G protein-coupled receptor 54; orphan G protein-coupled receptor GPR54; rOT7T175
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84634
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q969F8
• Gene Symbols: KISS1R
• Immunogen: Synthetic peptide encompassing a sequence within the Intracellular domain of human GPR54. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG