Invitrogen™ KISS1 Recombinant Rabbit Monoclonal Antibody (HL3043)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA556772

Product Code. 30275330

Description

KISS1 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH neurons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.

Specifications

• Antigen: KISS1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: Q15726
• Gene Symbols: KISS1
• Immunogen: Recombinant fragment of human Kiss1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: HL3043
• Conjugate: Unconjugated
• Gene: KISS1
• Gene Alias: 0610012C01Rik; Eseptin; HH13; KISS1; KiSS-1; KiSS-1 metastasis-suppressor; Kiss1 metastasis-suppressor; Kiss1 variant E1a-E2b-E3; Kiss1 variant E1b-E2a-E3; Kiss1 variant E1b-E2b-E3; kisspeptin; Kisspeptin-1; Kisspeptin-10; Kisspeptin-13; Kisspeptin-14; Kisspeptin-52; Kisspeptin-54; malignant melanoma metastasis-suppressor; metastasis-suppressor KiSS-1; metastatin; metastin; Metastin45-54; MLL septin-like fusion; PP5098; prepro-kisspeptin
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3814
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid