Invitrogen™ Kir7.1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5109875

Product Code. 17177803

Description

Immunogen sequence: IARPKNRAFS IRFTDTAVVA HMDGKPNLIF QVANTRPSPL TSVRVSAVLY QERENGKLYQ TSVDFHLDGI SSDECPFFIF PLTYYHSITP SSPLATLLQH ENPSHFELVV FLSAMQEGTG EICQRRTSYL PSEIMLHHCF ASLLTRGSKG EYQIKMENFD KTVPEFPTPL VSKSPNRTDL DIHINGQSID NFQISETGLT E.

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

Specifications

• Antigen: Kir7.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KCNJ13
• Gene Alias: Inward rectifier K(+) channel Kir7.1; inward rectifier potassium channel 13; Kcnj13; KIR1.4; KIR7.1; LCA16; Potassium channel, inwardly rectifying subfamily J member 13; potassium channel, inwardly rectifying subfamily J, member 13; potassium inwardly-rectifying channel, subfamily J, member 13; potassium voltage-gated channel subfamily J member 13; SVD
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100040591, 3769
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 2.56 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O60928, P86046
• Gene Symbols: KCNJ13
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human KCNJ13 (NP_002233.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG